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References Tran KL, Park YI, Pandya S, Muliyil NJ, Jensen BD, Huynh K, et al

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(2026) "Efficacy and safety of once-daily oral orforglipron compared with oral semaglutide in adults with type 2 diabetes (ACHIEVE-3): a multinational, multicentre, non-inferiority, open-label, randomised, phase 3 trial" The Lancet 2

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That wasnt at all surprising

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Some patients find that fresh, whole fruits satisfy their desire for sweetness more effectively than processed snacks, while others lose interest in fruit altogether during early dose escalation

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GPER (G-protein-coupled estrogen receptor)

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